Characteristic | Details |
---|---|
Active Ingredient | Sildenafil Citrate |
Dosage Forms | Caverta 50mg, Caverta 100mg |
Indication | Erectile Dysfunction |
Administration Route | Oral |
Half-Life | 3-5 Hours |
Onset of Action | 30-60 Minutes |
Learn More about Caverta |
Chemical Structure
The compound, sildenafil citrate, features a unique structure. This configuration enables its action on phosphodiesterase type 5 (PDE5). A purine-like ring fused with a pyrazole creates its active core. The molecular formula is C22H30N6O4S. This drug exhibits high solubility in water, enhancing its bioavailability. Its stereochemistry influences receptor binding, critical for efficacy.
Specific functional groups confer distinct pharmacokinetic properties. The molecule interacts selectively with PDE5. This selectivity reduces cross-reactivity, minimizing adverse effects. The compound’s affinity for binding sites defines its potency. Understanding these interactions illuminates its mechanism in treating erectile dysfunction.
Off-Label Uses
Caverta 100mg is not limited to erectile dysfunction. It finds application in pulmonary arterial hypertension. This off-label use capitalizes on its vasodilatory effects. It enhances blood flow, reducing pulmonary pressure. This benefit stems from PDE5 inhibition in the vascular system.
Other potential uses arise from its action on blood vessels. Studies suggest benefits in Raynaud’s phenomenon. Here, sildenafil 100mg improves microcirculation. The evidence supports its role in reducing symptomatic attacks. Ongoing research explores further cardiovascular implications.
Who Can and Cannot Take Caverta
Caverta 50mg suits many adult men facing erectile challenges. It supports those without contraindicating health conditions. Patients with stable cardiovascular status may consider it safe. A healthcare provider’s guidance remains crucial.
Not everyone can take this medication. Those with nitrates for angina must avoid it. It interacts dangerously, risking severe hypotension. Patients with severe liver impairment should refrain. Consideration is vital for those with recent strokes or heart attacks.
Caverta Interactions
Caverta 100mg may interact with several drugs. Nitrates pose the most significant risk. Alpha-blockers can also influence blood pressure. Combining these requires careful management.
Other drugs may alter its metabolism. CYP3A4 inhibitors like ketoconazole extend its effects. Caution applies when combining with these. Food and alcohol can impact absorption rates. A full stomach delays its onset.
Toxicity
Sildenafil toxicity remains low at therapeutic doses. Overdosage leads to pronounced adverse effects. Common symptoms include headaches and dizziness. Vision disturbances can also manifest.
Severe outcomes require immediate medical attention. An overdose exacerbates cardiovascular risks. Priapism, a prolonged erection, necessitates intervention. Maintaining the recommended dose mitigates these dangers.
Caverta for Sale Online
Caverta 50mg is available through various online platforms. Consumers should choose reputable sources. Quality assurance ensures safety and efficacy. Counterfeit products pose significant health risks.
Online availability offers convenience. Patients can access this medication discreetly. Consulting a healthcare professional before purchase remains essential. Proper use aligns with therapeutic goals and minimizes risks.
Data source:
- https://smdg.ro/2024/09/05/sindromul-kartagener-si-optiunile-de-tratament/
- https://safetyhillqa.com/2024/07/06/dermatitis-herpetiformis/
- https://nilkanthdham.org/addison-disease-understanding-the-link-with-nocturnal-enuresis/
- https://benelova.com/2024/05/31/osteocondritis-y-sus-desafios-terapeuticos/
- https://ossretenlazarevicprilike.edu.rs/istrazivanje-ukrstanja-tretmana-glinase-prestab-i-neuromielitis-optica/
- https://bookings.seleneseaviewapartment.com/utforska-effekten-av-flunitrazepam-pa-aggstockscancerbehandlare/
- https://dinamiks.si/2023/12/28/bolezen-lafora-vpogled-v-zdravljenje-in-izzive/
- https://lorenabuttgenbach.com/other/kadalex-exploring-pharmacokinetics-and-efficacy/
- https://eventproductionforumeast.com/netarsudil-helyi-szemeszeti-alkalmazas/
- https://tecnicocalderasmadrid.es/2023/12/25/eligard-en-el-tratamiento-del-cancer-de-prostata/
- https://nd-chem.com/polyendocrinopathies-and-the-vestibular-system/
- https://dziczejemy.pl/zespol-hamartomatyczny-i-kontrola-glikemii/
- https://www.la-cuisine-saive.be/cuisine-tendance/infection-a-ascaris-ascaridiase-une-analyse-approfondie.html